![]() ![]() However, assessments of Taenia solium seropositivity durability in patients with various neurocysticercosis types are lacking. Neurocysticercosis prevalence estimates often are based on serosurveys. Clinician and public awareness of CTS and efforts to prevent transmission are needed. Since the first report of CTS in Curitiba in 2011, sporotrichosis has increased substantially, indicating continuous disease transmission. The main clinical form of sporotrichosis was lymphocutaneous (63%), followed by localized cutaneous (24%), ocular (10%), multisite infections (3%), and cutaneous disseminated (<0.5%). Incidence increased from 0.3 cases/100,000 outpatient visit-years in 2011 to 21.4 cases/100,000 outpatient visit-years in 2021 of the 216 cases, 58% (n = 126) were diagnosed during 2019–2021. Proven sporotrichosis was established in 84 (39%) patients and probable sporotrichosis in 132 (61%). We calculated incidence and mapped geographic distribution of cases in Curitiba, Brazil, by reviewing medical records from 216 sporotrichosis cases diagnosed during 2011–May 2022. ![]() We examined and described the emergence of cat-transmitted sporotrichosis (CTS) caused by the fungal pathogen Sporothrix brasiliensis. Zoonotic outbreaks of sporotrichosis are increasing in Brazil. Factors predictive of higher peak values and longer time to seroreversion included increasing age, male sex, higher body mass index, and non-Caucasian race. Within the cohort, only 0.75% of persons became seronegative. The observed peak signal-to-cutoff value varied widely, but the waning rate was consistent across the range, with a half-life of 122 days. We analyzed overall signal-to-cutoff values for 48,330 donations (average 2.5 donations/person) that had an average observation period of 102 days. We longitudinally evaluated a cohort of 19,323 blood donors who had evidence of recent infection by using a widely available serologic test to determine the dynamics of such waning. Antibodies to the nucleocapsid protein of SARS-CoV-2 indicate previous infection but are subject to waning, potentially affecting epidemiologic studies. We evaluated antibodies to the nucleocapsid protein of SARS-CoV-2 in a large cohort of blood donors in the United States who were recently infected with the virus. 18S gene sequencing and amplified length polymorphism analysis revealed distinct clustering of R. homothallicus against the commonly used antifungals (amphotericin B, itraconazole, posaconazole, and isavuconazole ). We also performed antifungal-susceptibility testing, which indicated a low range of MICs for R. ![]() 104/266 ) after adjusting for age, intracranial involvement, and surgery. homothallicus infection was independently associated with better survival (odds ratio 0.08 p = 0.001) than for R. homothallicus accounted for 43 (6.8%) of the 631 cases of mucormycosis. homothallicus infection and the 30-day mortality rate in rhino-orbital mucormycosis attributable to R. The objectives were ascertaining the proportion of R. We retrospectively reviewed consecutive cases of mucormycosis reported from a tertiary-care center in India to determine the clinical and mycologic characteristics of emerging Rhizopus homothallicus fungus. ![]()
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